Aurorus / Applications / Research & Clinical Trials
§ 01 / Research & Clinical Trials

A measurement layer for studies that find — and trials that prove.

One non-invasive scan, forty-nine channels, under seven minutes. For research, that means a fuller picture of every participant and far more data to build hypotheses around. For trials, a clearer read on whether a therapy is working — and earlier warning when it isn't safe.

Non-invasive Seven-minute read 49 channels No phlebotomy Serial-friendly Decentralized-ready
§ 02
The measurement question

The instrument stays the same. The question changes.

Aurorus was built as a measurement layer, not for any one study design. A non-invasive scan, under seven minutes, no phlebotomy — producing a quantitative read of physiological state across forty-nine channels.

Research and trials ask different things of that read. Studies want breadth — more dimensions, captured more often, on more participants. Trials want decision quality and safety — a clearer answer on efficacy, and an earlier one on harm.

§ 03
Track A · Research studies

Research studies with a more complete data profile.

In research the constraint has rarely been ideas. It's data — its breadth, its frequency, and the friction of collecting it. Aurorus has the potential to loosen all three at once.

Capability · 01

A comprehensive physiological picture

A single read resolves activity across forty-nine anatomical channels at once — a system-level portrait of the participant rather than a handful of isolated analytes. Studies capture the whole physiological surface in one pass, including dimensions that single-marker assays were never designed to see.

49 channelsSystem-levelOne pass
Capability · 02

More data, captured more often

Because the scan is non-invasive and takes minutes, dense longitudinal sampling becomes practical — weekly, daily, or before-and-after a single exposure, at frequencies that serial blood draws make cost- and burden-prohibitive. Studies trade sparse snapshots for a continuous physiological trajectory.

LongitudinalHigh-frequencyPaired reads
Capability · 03

Hypotheses you couldn't build before

A high-dimensional, repeatable readout is fertile ground for discovery. Researchers can surface patterns and correlations across channels, cohorts, and time — generating hypotheses from the data itself, then testing them on the same instrument that raised them. Findings stay comparable across studies, sites, and populations.

DiscoveryMultidimensionalComparable
Capability · 04

Lower friction, larger cohorts

Non-invasive, portable, and operable without a phlebotomist, the scan reaches participants who decline or can't tolerate blood draws — and runs in homes, remote sites, and decentralized arms. Lower participant burden means better retention and bigger, more representative cohorts.

DecentralizedRemote sitesRetention
Research instrumentation — every participant, every visit

Every participant, at every visit, leaves behind a forty-nine-channel physiological record — not a single lab value, but a structured, archivable, comparable map of state. The hypothesis you'll want to test next year is already in the data you collect today.

Where it fits · 01 Observational & cohort studies

Dense, low-burden monitoring across long follow-up — where conventional retesting frequency is the limiting factor on what the study can observe.

Where it fits · 02 Mechanistic & exploratory work

A multidimensional readout to characterize how a state or exposure moves physiology — and to surface candidate signals worth a dedicated study.

Where it fits · 03 Registries & real-world data

A consistent measurement standard across sites and populations, so records collected years and continents apart remain comparable.

§ 04
Track B · Clinical trials

Making clinical trials more robust, safer, and cost-effective.

The same measurement, pointed at the questions a trial lives and dies by — does the therapy work, and is it safe.

Pilot · Research partners — measurement endpoint, not a diagnostic claim

Aurorus has the potential to make clinical trials more robust, safer, and more cost-effective. The scan could give sponsors a clearer picture of whether a therapy is working — and may be able to catch safety signals earlier, before adverse effects reach clinical thresholds.

The aim is for trials to reach decisions on stronger evidence, with less risk to participants and less capital spent on candidates that aren't performing.

§ 04 ·
Three ways it changes the trial

Stronger evidence, earlier warning, lower spend.

01 · Robust

A clearer efficacy signal.

A quantitative, multidimensional read of physiological response — captured before, during, and after intervention on the same instrument. Sponsors could see whether a therapy is actually moving the participant, beyond what a single endpoint or self-report reveals — with the aim of helping trials reach decisions on stronger evidence.

02 · Safer

Safety signals, caught earlier.

Because the scan can register physiological change before it surfaces as a clinical event, it may be able to flag deterioration earlier — potentially before adverse effects reach clinical thresholds, giving investigators a chance to intervene, adjust, or stop sooner, with less risk to participants.

03 · Cost-effective

Less capital on the wrong candidates.

Earlier, clearer signal could mean less money spent carrying under-performing candidates through expensive late phases. Non-invasive, decentralized-ready scans also cut per-visit assessment cost and the logistics of serial blood collection across the cohort.

§ 04 ·
Across the lifecycle

Useful at every phase.

The same paired-read protocol fits wherever a trial needs to know what a therapy is doing to the participant.

One protocol · early phase through real-world follow-up
Phase · I Safety & dose-finding

Dense physiological monitoring of early cohorts — aiming to help surface tolerability signals before they escalate, and to inform dose decisions with more than vitals and labs alone.

Phase · II Signal-finding

A sensitive, multidimensional efficacy read aimed at detecting whether a therapy is working and in whom — to help sharpen go / no-go decisions before committing to pivotal scale.

Phase · III & IV Confirmatory & real-world

A consistent, decentralized-ready endpoint across large, distributed cohorts — extending into post-market and registry follow-up on the same measurement standard.

§ 05
For the record

What the instrument is, in research.

For the record · placed deliberately FDA De Novo · DEN150004
Aurorus is
  • An FDA De Novo cleared (DEN150004) electrophysiological measurement tool that provides quantitative data on electrophysiological and related bioelectric signals.
  • A general wellness and research tool that offers insights into an individual’s physiological and autonomic nervous system activity.
  • A fast, non-invasive way to track changes over time in response to wellness practices, lifestyle interventions, and other therapies.
  • A complementary technology designed to support practitioners in functional and integrative settings.
Aurorus is not
  • A diagnostic device for any specific disease or medical condition.
  • A replacement for conventional medical diagnostics, imaging (MRI, CT), or clinical laboratory testing.
  • Immune to all biological variability — factors such as age, medications, recent meals, and acute states can influence readings and must be considered in context.
  • Intended to diagnose, treat, cure, or prevent any disease.
  • A standalone clinical decision-making tool — results should always be interpreted by qualified practitioners alongside other clinical findings.
§ 06
Next steps

Bring it into your study.

Tell us what you're investigating. We'll route the conversation to the right person on our research team.

Aurorus is an electrophysiological measurement system cleared by the FDA under De Novo classification (DEN150004). It is not an in-vitro diagnostic and does not replace clinical judgment, protocol-defined primary endpoints, or laboratory testing where required. Use of Aurorus measurements as a study endpoint is determined by the investigator and study protocol.